Care Diagnostic Center


Saline infusion sonohysterography (SIS) or saline ultrasound uterine scan is a test where a small volume of saline (salt solution) is inserted into the uterus (or womb). This allows the lining of the uterus (endometrium) to be clearly seen on an ultrasound scan. It is also known as a saline ultrasound uterine scan. “Ultrasound” is the term used for an imaging test that uses high frequency soundwaves. SIS helps to see if there is any thickening of the endometrium of the uterus, or if there are polyps. Polyps are small growths of the endometrium. The scan can also be performed in the assessment of post menopausal endometrium or possible Asherman’s Syndrome (a condition caused by the presence of scars in the uterine cavity).

Indications include but are not limited to evaluation of:

  • Uterine cavity, especially with regard to uterine myomas, polyps, and synechiae.
  • Abnormalities detected on endovaginal sonography, including focal or diffuse endometrial or intracavitary abnormalities.
  • Uterine cavity, especially with regard to uterine myomas, polyps, and synechiae.
  • Infertility & recurrent pregnancy loss.
  • Suboptimal visualization of the endometrium on endovaginal ultrasound.


Your doctor may request this test for a number of reasons, including:

  • We Looking for a lesion in the endometrium, such as a polyp. You may have a pelvic ultrasound that suggests the endometrium is thicker than normal or has a different appearance. The saline sonohysterogram will help confirm or exclude the presence of an endometrial polyp or submucous fibroid.
  • Investigation of postmenopausal bleeding, especially if the endometrium is not well seen on a regular pelvic ultrasound, or if the endometrium appears thicker than expected.
  • Assessing the shape of the endometrial cavity. The saline sonohysterogram evaluates the contour of the endometrial cavity, detecting conditions such as a uterine septum or bicornuate uterus (these are types of congenital uterine anomalies). 3D/4D imaging of the uterus during the sonohysterogram is particularly useful for the assessment of congenital uterine anomalies. This information may be used to investigate problems like recurrent miscarriages or infertility.


  • You do not need a full bladder for this test, unless you are also booked for a pelvic ultrasound on the same day. We will ask you to completely empty your bladder before the test begins.
  • You can eat and drink normally before and after the test.